Usage:Use an oil free moisturizer before application. Twist to open the tube and use a small amount of serum to dab ( do not rub) on target areas, eye area, smile lines, neck or forehead and let dry. Use oil-free products on top. Close the tube immediately by reversing the cap to prevent drying out and to allow reuse of the product. Tip: If you see a white film appear, you've applied to much. Wash off with oil-based cleanser and reapply. Caution: Do not apply directly to eye, do not ingest. Carry out patch test 24 hours before use.